• StephenC.Benoit, PhD, MA, LPC
  • COM Psychiatry Basic Research
  • Associate Professor of Psychiatry and Behavioral Neuroscience, Director of Continuing Medical Education
  • 513-558-4312
  • Academic Location:
    Stetson Building

    Cincinnati, OH 45219
  • 513-558-4312
  • stephen.benoit@uc.edu

Professional Summary

  • STEPHEN C. BENOIT, PH.D.

    My research interests focus on neurobiological controls over behavior with emphases on food intake and learning. Part of this work has centered on the molecular, physiological and behavioral effects of hypothalamic neuropeptides that influence energy homeostasis, and how these neurotransmitters are modified by signals proportional to the amount of fat in the body (e.g., the hormones, leptin and insulin). Other studies have focused on the role of learning in the control of ingestive behavior. At the risk of oversimplifying the situation, influences on food intake can be categorized as homeostatic (e.g., related to body weight) and non-homeostatic (e.g., related to visceral illness, hedonics or the incentive value of food.) Long-term research goals of mine are to determine which specific learning processes are critical for the maintenance of energy balance as well as how disrupted energy balance (e.g., obesity) influences the neurobiology of learning.

Research/Clinical Interests

  • Research focus is on obesity and neurobiological controls over behavior with emphases on food intake and learning.

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Research Grants
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  • 2004-2008. Central Syndecans in CNS Melanocortin Regulation of Energy Balance, P.I.
  • 2004-2008. Behavioral Mechanisms of CNS Melanocortin Action, P.I.
  • 2005. Health Alliance / University Hospital grant for Neuroscience. Depressive Disorders and Cognitive Impairments as Predictors of Stroke Outcome, Co. I.
  • 2006-2010. Molecular Connections Between Arousal and Metabolic Disease: Orexin and Modafinil, Benoit, PI
  • 2006-2011. High Fat Diet-Induced Obesity, Project 1 Co-I and Animal Core, Director
  • 2007-2012. Energy Disregulation: Behavioral and Biological Signals
  • 2008-2011. Novel Obesity Therapies
  • 2008-2010. Antipsychotics, hypoglycemia, glutamate and cognition
  • 2008-2010. Selective DAT Inhibitor for Treatment of Obesity
  • 5-R01-DK-066223-03-A0-S0-E008/01/2004-07/31/2008. National Inst of Diabetes and Digestive and Kidney Disease. Behavioral Mechanisms of CNS Melanocortin Action, PI, Closed.
  • W81XWH-06-2-001903/27/2006-03/26/2010. Department of the Army Medical Research Acquisition Activity. Molecular connection Between Arousal and Metabolic Disease: Orexin and Modafinil, PI, Closed.
  • R01-DK-06488504/01/2004-03/31/2008. National Inst of Diabetes and Digestive and Kidney Disease. Syndecan Regulation of CNS Melanocortin Signaling in Energy Balance, PI, Closed.
  • 5-R03-MH-65353-02-A0-S0-E005/01/2002-04/30/2004. National Institute of Mental Health. Role of CNS Insulin in Learning and Memory, PI, Closed.
  • 5-F32-DK-10032-03-A0-S0-E002/01/2000-03/31/2002. National Inst of Diabetes and Digestive and Kidney Disease. Interaction of CNS Insulin and Melanocortin Systems, PI, Closed.
  • P30 AG1013308/01/2006-06/30/2009. National Institute on Aging. Energy Metabolism and Cognitive Aging, Collaborator, Active.
  • 4102-24430 / P01 HD052112-01A209/17/2007-06/30/2012. National Institute of Child Health and Human Development. Energy Dysregulation: Behavioral and Biological Signals, PI, Active.
  • 0000169328 / FA8650-05-651810/13/2007-12/31/2010. Department of the Air Force. Studies on Pathologies of Interest to the Air Force Research Lab, Collaborator, Closed.
  • SRS 00543701/23/2008-01/22/2014. Ethicon Endo Surgery, Incorporated. New Therapeutic Strategies for Obesity, Collaborator, Active.
  • R43 DK08129307/01/2008-05/31/2010. National Inst of Diabetes and Digestive and Kidney Disease. Selective DAT Inhibitor for Treatment of Obesity, PI, Closed.
  • 1R21MH083192-01A108/20/2008-07/31/2011. National Institute of Mental Health. Antipsychotics, Hypoglycemia, Glutamate and Cognition, Collaborator, Closed.
  • 10010102 / 5 R43 DK083767-01A105/01/2010-04/30/2012. National Inst of Diabetes and Digestive and Kidney Disease. Y2 and Y4 Agonists in Obesity, PI, Closed.
  • 10060843 / R43 DK08584708/01/2010-07/31/2012. National Inst of Diabetes and Digestive and Kidney Disease. TNF Inhibitor PD2024 (6 Groups) and VEH (2 Groups), PI, Closed.
  • VA IPA 2010-1404/01/2011-03/31/2013. Department of Veterans Affairs. Intergovernmental Personnel Act Agreement for Stephen Benoit, PI, Closed.
  • SRS 00725312/17/2010-12/17/2013. Pfizer, Inc.. Obesity Drug Target Identification, Collaborator, Closed.
  • 706924 / FA8650-10-2-606201/01/2011-12/31/2012. Air Force Research Laboratory. Regulation of Biomarkers of Cognitive Enhancement by Nutrient Modulation of mTORC1 Signaling, Collaborator, Closed.
  • R44DK081293 (SBIR Phase II)07/01/2011-06/30/2013. National Inst of Diabetes and Digestive and Kidney Disease. DAT Inhibitor for the Treatment of Obesity, PI, Active.
  • U24 DK05963009/16/2011-06/30/2016. National Inst of Diabetes and Digestive and Kidney Disease. Cincinnati Mouse Metabolic Phenotyping Center, Collaborator, Active.
  • R21DA03187607/15/2012-03/31/2014. National Institute on Drug Abuse. Conditioned Place Preference to Amphetamine Following Prenatal Immune Activation, Collaborator, Active.
  • F31MH09743009/16/2012-09/15/2014. National Institute of Mental Health. Prefrontal GR Signaling and Memory, Collaborator, Active.
  • 08818-01-311642 / R21 DA03187607/01/2013-03/31/2014. National Institute on Drug Abuse. Conditioned Place Preference to Amphetamine following Prenatal Immune Activation, Collaborator, Awarded.
  • U2CDK05963008/01/2016-06/30/2021. National Inst of Diabetes and Digestive and Kidney Disease. Cincinnati Mouse Metabolic Phenotyping Center , Collaborator, Active.
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Peer Reviewed Publications (in chronological order)
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  • Ivezaj, V., Stoeckel, L. E., Avena, N. M., Benoit, S. C., Conason, A., Davis, J. F., Gearhardt, A. N., Goldman, R., Mitchell, J. E., Ochner, C. N., Saules, K. K., Steffen, K. J., Stice, E., & Sogg, S. (2017). Obesity and addiction: can a complication of surgery help us understand the connection?. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. doi:10.1111/obr.12542
  • Smith, B. L., Lyons, C. E., Correa, F. G., Benoit, S. C., Myers, B., Solomon, M. B., & Herman, J. P. (2017). Behavioral and physiological consequences of enrichment loss in rats.. Psychoneuroendocrinology, 77, 37-46. doi:10.1016/j.psyneuen.2016.11.040
  • Sirohi, S., Schurdak, J. D., Seeley, R. J., Benoit, S. C., & Davis, J. F. (2016). Central & peripheral glucagon-like peptide-1 receptor signaling differentially regulate addictive behaviors.. Physiology & Behavior, 161, 140-4. doi:10.1016/j.physbeh.2016.04.013
  • Tracy, A. L., Schurdak, J. D., Chambers, J. B., & Benoit, S. C. (2016). Aversion learning can reduce meal size without taste avoidance in rats.. Obesity (Silver Spring, Md.), 24 (3), 606-14. doi:10.1002/oby.21379
  • Inge, T. H., Prigeon, R. L., Elder, D. A., Jenkins, T. M., Cohen, R. M., Xanthakos, S. A., Benoit, S. C., Dolan, L. M., Daniels, S. R., & D'Alessio, D. A. (2015). Insulin Sensitivity and ?-Cell Function Improve after Gastric Bypass in Severely Obese Adolescents.. The Journal of Pediatrics, 167 (5), 1042-8.e1. doi:10.1016/j.jpeds.2015.08.020
  • Müller, T. D., Nogueiras, R., Andermann, M. L., Andrews, Z. B., Anker, S. D., Argente, J., Batterham, R. L., Benoit, S. C., Bowers, C. Y., Broglio, F., Casanueva, F. F., D'Alessio, D., Depoortere, I., Geliebter, A., Ghigo, E., Cole, P. A., Cowley, M., Cummings, D. E., Dagher, A., Diano, S., Dickson, S. L., Diéguez, C., Granata, R., Grill, H. J., Grove, K., Habegger, K. M., Heppner, K., Heiman, M. L., Holsen, L., Holst, B., Inui, A., Jansson, J. O., Kirchner, H., Korbonits, M., Laferrère, B., LeRoux, C. W., Lopez, M., Morin, S., Nakazato, M., Nass, R., Perez-Tilve, D., Pfluger, P. T., Schwartz, T. W., Seeley, R. J., Sleeman, M., Sun, Y., Sussel, L., Tong, J., Thorner, M. O., van der Lely, A. J., van der Ploeg, L. H. T., Zigman, J. M., Kojima, M., Kangawa, K., Smith, R. G., Horvath, T., & Tschöp, M. H. (2015). Ghrelin.. Molecular Metabolism, 4 (6), 437-60. doi:10.1016/j.molmet.2015.03.005
  • Jury, N. J., McCormick, B. A., Horseman, N. D., Benoit, S. C., & Gregerson, K. A. (2015). Enhanced responsiveness to selective serotonin reuptake inhibitors during lactation.. PloS One, 10 (2), e0117339. doi:10.1371/journal.pone.0117339
  • Benoit, S. C., Hunter, T. D., Francis, D. M., & De La Cruz-Munoz, N. (2014). Use of Bariatric Outcomes Longitudinal Database (BOLD) to Study Variability in Patient Success After Bariatric Surgery.. Obesity Surgery. doi:10.1007/s11695-014-1197-y
  • Tong, J., Davis, H. W., Summer, S., Benoit, S. C., Haque, A., Bidlingmaier, M., Tschöp, M. H., & D'Alessio, D. (2014). Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans.. Diabetes. doi:10.2337/db13-1598
  • Habegger, K. M., Heppner, K. M., Amburgy, S. E., Ottaway, N., Holland, J., Raver, C., Bartley, E., Müller, T. D., Pfluger, P. T., Berger, J., Toure, M., Benoit, S. C., Dimarchi, R. D., Perez-Tilve, D., D'Alessio, D. A., Seeley, R. J., & Tschöp, M. H. (2014). GLP-1R Responsiveness Predicts Individual Gastric Bypass Efficacy on Glucose Tolerance in Rats.. Diabetes, 63 (2), 505-13. doi:10.2337/db13-0511
  • Grayson, B. E., Hakala-Finch, A. P., Kekulawala, M., Laub, H., Egan, A. E., Ressler, I. B., Woods, S. C., Herman, J. P., Seeley, R. J., Benoit, S. C., & Ulrich-Lai, Y. M. (2014). Weight loss by calorie restriction versus bariatric surgery differentially regulates the hypothalamo-pituitary-adrenocortical axis in male rats.. Stress (Amsterdam, Netherlands), 17 (6), 484-93. doi:10.3109/10253890.2014.967677
  • Picard, A., Rouch, C., Kassis, N., Moullé, V. S., Croizier, S., Denis, R. G., Castel, J., Coant, N., Davis, K., Clegg, D. J., Benoit, S. C., Prévot, V., Bouret, S., Luquet, S., Le Stunff, H., Cruciani-Guglielmacci, C., & Magnan, C. (2014). Hippocampal lipoprotein lipase regulates energy balance in rodents.. Molecular Metabolism, 3 (2), 167-76. doi:10.1016/j.molmet.2013.11.002
  • Davis, J. F., & Benoit, S. C. (2013). Response to Hajnal et al.. Obesity Surgery, 23 (8), 1318. doi:10.1007/s11695-013-0962-7
  • Davis, J. F., Tracy, A. L., Schurdak, J. D., Magrisso, I. J., Grayson, B. E., Seeley, R. J., & Benoit, S. C. (2013). Roux en Y gastric bypass increases ethanol intake in the rat.. Obesity Surgery, 23 (7), 920-30. doi:10.1007/s11695-013-0884-4
  • Grayson, B. E., Fitzgerald, M. F., Hakala-Finch, A. P., Ferris, V. M., Begg, D. P., Tong, J., Woods, S. C., Seeley, R. J., Davidson, T. L., & Benoit, S. C. (2013). Improvements in hippocampal-dependent memory and microglial infiltration with calorie restriction and gastric bypass surgery, but not with vertical sleeve gastrectomy.. International Journal of Obesity (2005). doi:10.1038/ijo.2013.100
  • Isom, A. M., Gudelsky, G. A., Benoit, S. C., & Richtand, N. M. (2013). Antipsychotic medications, glutamate, and cell death: a hidden, but common medication side effect?. Medical Hypotheses, 80 (3), 252-8. doi:10.1016/j.mehy.2012.11.042
  • Figlewicz, D. P., Jay, J. L., Acheson, M. A., Magrisso, I. J., West, C. H., Zavosh, A., Benoit, S. C., & Davis, J. F. (2013). Moderate high fat diet increases sucrose self-administration in young rats.. Appetite, 61 (1), 19-29. doi:10.1016/j.appet.2012.09.021
  • Wilson-Pérez, H. E., Chambers, A. P., Sandoval, D. A., Stefater, M. A., Woods, S. C., Benoit, S. C., & Seeley, R. J. (2013). The effect of vertical sleeve gastrectomy on food choice in rats.. International Journal of Obesity (2005), 37 (2), 288-95. doi:10.1038/ijo.2012.18
  • Davis, J. F., Perello, M., Choi, D. L., Magrisso, I. J., Kirchner, H., Pfluger, P. T., Tschoep, M., Zigman, J. M., & Benoit, S. C. (2012). GOAT induced ghrelin acylation regulates hedonic feeding.. Hormones and Behavior, 62 (5), 598-604. doi:10.1016/j.yhbeh.2012.08.009
  • McNamara, R. K., Magrisso, I. J., Hofacer, R., Jandacek, R., Rider, T., Tso, P., & Benoit, S. C. (2012). Omega-3 fatty acid deficiency augments risperidone-induced hepatic steatosis in rats: positive association with stearoyl-CoA desaturase.. Pharmacological Research : the Official Journal of the Italian Pharmacological Society, 66 (4), 283-91. doi:10.1016/j.phrs.2012.06.010
  • Davis, J. F., Schurdak, J. D., Magrisso, I. J., Mul, J. D., Grayson, B. E., Pfluger, P. T., Tschöp, M. H., Seeley, R. J., & Benoit, S. C. (2012). Gastric bypass surgery attenuates ethanol consumption in ethanol-preferring rats.. Biological Psychiatry, 72 (5), 354-60. doi:10.1016/j.biopsych.2012.01.035
  • Kurosawa, Y., Degrauw, T. J., Lindquist, D. M., Blanco, V. M., Pyne-Geithman, G. J., Daikoku, T., Chambers, J. B., Benoit, S. C., & Clark, J. F. (2012). Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency.. The Journal of Clinical Investigation, 122 (8), 2837-46. doi:10.1172/JCI59373
  • Choi, D. L., Davis, J. F., Magrisso, I. J., Fitzgerald, M. E., Lipton, J. W., & Benoit, S. C. (2012). Orexin signaling in the paraventricular thalamic nucleus modulates mesolimbic dopamine and hedonic feeding in the rat.. Neuroscience, 210, 243-8. doi:10.1016/j.neuroscience.2012.02.036
  • Castañeda, T. R., Abplanalp, W., Um, S. H., Pfluger, P. T., Schrott, B., Brown, K., Grant, E., Carnevalli, L., Benoit, S. C., Morgan, D. A., Gilham, D., Hui, D. Y., Rahmouni, K., Thomas, G., Kozma, S. C., Clegg, D. J., & Tschöp, M. H. (2012). Metabolic control by S6 kinases depends on dietary lipids.. PloS One, 7 (3), e32631. doi:10.1371/journal.pone.0032631
  • Yi, C., Heppner, K. M., Kirchner, H., Tong, J., Bielohuby, M., Gaylinn, B. D., Müller, T. D., Bartley, E., Davis, H. W., Zhao, Y., Joseph, A., Kruthaupt, T., Ottaway, N., Kabra, D., Habegger, K. M., Benoit, S. C., Bidlingmaier, M., Thorner, M. O., Perez-Tilve, D., Tschöp, M. H., & Pfluger, P. T. (2012). The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction.. PloS One, 7 (2), e32100. doi:10.1371/journal.pone.0032100
  • Summer, S. S., Brehm, B. J., Benoit, S. C., & D'Alessio, D. A. (2011). Adiponectin changes in relation to the macronutrient composition of a weight-loss diet.. Obesity (Silver Spring, Md.), 19 (11), 2198-204. doi:10.1038/oby.2011.60
  • Hofacer, R., Jack Magrisso, I., Jandacek, R., Rider, T., Tso, P., Benoit, S. C., & McNamara, R. K. (2011). Omega-3 fatty acid deficiency increases stearoyl-CoA desaturase expression and activity indices in rat liver: Positive association with non-fasting plasma triglyceride levels.. Prostaglandins, Leukotrienes, and Essential Fatty Acids. doi:10.1016/j.plefa.2011.10.003
  • Hofacer, R., Jandacek, R., Rider, T., Tso, P., Magrisso, I. J., Benoit, S. C., & McNamara, R. K. (2011). Omega-3 fatty acid deficiency selectively up-regulates delta6-desaturase expression and activity indices in rat liver: prevention by normalization of omega-3 fatty acid status.. Nutrition Research (New York, N.Y.), 31 (9), 715-22. doi:10.1016/j.nutres.2011.08.007
  • Krawczewski Carhuatanta, K. A., Demuro, G., Tschöp, M. H., Pfluger, P. T., Benoit, S. C., & Obici, S. (2011). Voluntary exercise improves high-fat diet-induced leptin resistance independent of adiposity.. Endocrinology, 152 (7), 2655-64. doi:10.1210/en.2010-1340
  • Irani, B. G., Xiang, Z., Yarandi, H. N., Holder, J. R., Moore, M. C., Bauzo, R. M., Proneth, B., Shaw, A. M., Millard, W. J., Chambers, J. B., Benoit, S. C., Clegg, D. J., & Haskell-Luevano, C. (2011). Implication of the melanocortin-3 receptor in the regulation of food intake.. European Journal of Pharmacology, 660 (1), 80-7. doi:10.1016/j.ejphar.2010.10.101
  • Clegg, D. J., Gotoh, K., Kemp, C., Wortman, M. D., Benoit, S. C., Brown, L. M., D'Alessio, D., Tso, P., Seeley, R. J., & Woods, S. C. (2011). Consumption of a high-fat diet induces central insulin resistance independent of adiposity.. Physiology & Behavior, 103 (1), 10-6. doi:10.1016/j.physbeh.2011.01.010
  • Davis, J. F., Choi, D. L., Clegg, D. J., & Benoit, S. C. (2011). Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice.. Physiology & Behavior, 103 (1), 39-43. doi:10.1016/j.physbeh.2010.10.017
  • Davis, J. F., Choi, D. L., Schurdak, J. D., Fitzgerald, M. F., Clegg, D. J., Lipton, J. W., Figlewicz, D. P., & Benoit, S. C. (2011). Leptin regulates energy balance and motivation through action at distinct neural circuits.. Biological Psychiatry, 69 (7), 668-74. doi:10.1016/j.biopsych.2010.08.028
  • Davis, J. F., Choi, D. L., Shurdak, J. D., Krause, E. G., Fitzgerald, M. F., Lipton, J. W., Sakai, R. R., & Benoit, S. C. (2011). Central melanocortins modulate mesocorticolimbic activity and food seeking behavior in the rat.. Physiology & Behavior, 102 (5), 491-5. doi:10.1016/j.physbeh.2010.12.017
  • Zheng, Q., Zhu, J., Shanabrough, M., Borok, E., Benoit, S. C., Horvath, T. L., Clegg, D. J., & Reizes, O. (2010). Enhanced anorexigenic signaling in lean obesity resistant syndecan-3 null mice.. Neuroscience, 171 (4), 1032-40. doi:10.1016/j.neuroscience.2010.09.060
  • Krikorian, R., Shidler, M. D., Dangelo, K., Couch, S. C., Benoit, S. C., & Clegg, D. J. (2010). Dietary ketosis enhances memory in mild cognitive impairment.. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2010.10.006
  • Benoit, S. C., Davis, J. F., & Davidson, T. L. (2010). Learned and cognitive controls of food intake.. Brain Research, 1350, 71-6. doi:10.1016/j.brainres.2010.06.009
  • Perez-Tilve, D., Hofmann, S. M., Basford, J., Nogueiras, R., Pfluger, P. T., Patterson, J. T., Grant, E., Wilson-Perez, H. E., Granholm, N. A., Arnold, M., Trevaskis, J. L., Butler, A. A., Davidson, W. S., Woods, S. C., Benoit, S. C., Sleeman, M. W., DiMarchi, R. D., Hui, D. Y., & Tschöp, M. H. (2010). Melanocortin signaling in the CNS directly regulates circulating cholesterol.. Nature Neuroscience, 13 (7), 877-82. doi:10.1038/nn.2569
  • Choi, D. L., Davis, J. F., Fitzgerald, M. E., & Benoit, S. C. (2010). The role of orexin-A in food motivation, reward-based feeding behavior and food-induced neuronal activation in rats.. Neuroscience, 167 (1), 11-20. doi:10.1016/j.neuroscience.2010.02.002
  • Davidson, T. L., Kanoski, S. E., Chan, K., Clegg, D. J., Benoit, S. C., & Jarrard, L. E. (2010). Hippocampal lesions impair retention of discriminative responding based on energy state cues.. Behavioral Neuroscience, 124 (1), 97-105. doi:10.1037/a0018402
  • Davis, J. F., Choi, D. L., & Benoit, S. C. (2010). Insulin, leptin and reward.. Trends in Endocrinology and Metabolism: TEM, 21 (2), 68-74. doi:10.1016/j.tem.2009.08.004
  • Thaler, J. P., Choi, S. J., Sajan, M. P., Ogimoto, K., Nguyen, H. T., Matsen, M., Benoit, S. C., Wisse, B. E., Farese, R. V., & Schwartz, M. W. (2009). Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses.. Endocrinology, 150 (12), 5362-72. doi:10.1210/en.2009-0509
  • Benoit, S. C., Kemp, C. J., Elias, C. F., Abplanalp, W., Herman, J. P., Migrenne, S., Lefevre, A., Cruciani-Guglielmacci, C., Magnan, C., Yu, F., Niswender, K., Irani, B. G., Holland, W. L., & Clegg, D. J. (2009). Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents.. The Journal of Clinical Investigation, 119 (9), 2577-89. doi:10.1172/JCI36714
  • Davis, J. F., Krause, E. G., Melhorn, S. J., Sakai, R. R., & Benoit, S. C. (2009). Dominant rats are natural risk takers and display increased motivation for food reward.. Neuroscience, 162 (1), 23-30. doi:10.1016/j.neuroscience.2009.04.039
  • Thompson, V. B., Heiman, J., Chambers, J. B., Benoit, S. C., Buesing, W. R., Norman, M. K., Norman, A. B., & Lipton, J. W. (2009). Long-term behavioral consequences of prenatal MDMA exposure.. Physiology & Behavior, 96 (4-5), 593-601. doi:10.1016/j.physbeh.2008.12.013
  • Davidson, T. L., Chan, K., Jarrard, L. E., Kanoski, S. E., Clegg, D. J., & Benoit, S. C. (2009). Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation.. Hippocampus, 19 (3), 235-52. doi:10.1002/hipo.20499
  • Figlewicz, D. P., & Benoit, S. C. (2009). Insulin, leptin, and food reward: update 2008.. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 296 (1), R9-R19. doi:10.1152/ajpregu.90725.2008
  • Davis, J. F., Tracy, A. L., Schurdak, J. D., Tschöp, M. H., Lipton, J. W., Clegg, D. J., & Benoit, S. C. (2008). Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat.. Behavioral Neuroscience, 122 (6), 1257-63. doi:10.1037/a0013111
  • Krause, E. G., Melhorn, S. J., Davis, J. F., Scott, K. A., Ma, L. Y., de Kloet, A. D., Benoit, S. C., Woods, S. C., & Sakai, R. R. (2008). Angiotensin type 1 receptors in the subfornical organ mediate the drinking and hypothalamic-pituitary-adrenal response to systemic isoproterenol.. Endocrinology, 149 (12), 6416-24. doi:10.1210/en.2008-0477
  • Benoit, S. C., Tracy, A. L., Davis, J. F., Choi, D., & Clegg, D. J. (2008). Novel functions of orexigenic hypothalamic peptides: from genes to behavior.. Nutrition (Burbank, Los Angeles County, Calif.), 24 (9), 843-7. doi:10.1016/j.nut.2008.06.028
  • Nogueiras, R., López, M., Lage, R., Perez-Tilve, D., Pfluger, P., Mendieta-Zerón, H., Sakkou, M., Wiedmer, P., Benoit, S. C., Datta, R., Dong, J. Z., Culler, M., Sleeman, M., Vidal-Puig, A., Horvath, T., Treier, M., Diéguez, C., & Tschöp, M. H. (2008). Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability.. Endocrinology, 149 (6), 3009-15. doi:10.1210/en.2007-1684
  • Tracy, A. L., Clegg, D. J., Johnson, J. D., Davidson, T. L., & Benoit, S. C. (2008). The melanocortin antagonist AgRP (83-132) increases appetitive responding for a fat, but not a carbohydrate, reinforcer.. Pharmacology, Biochemistry, and Behavior, 89 (3), 263-71. doi:10.1016/j.pbb.2007.12.018
  • Reed, J. A., Benoit, S. C., Pfluger, P. T., Tschöp, M. H., D'Alessio, D. A., & Seeley, R. J. (2008). Mice with chronically increased circulating ghrelin develop age-related glucose intolerance.. American Journal of Physiology. Endocrinology and Metabolism, 294 (4), E752-60. doi:10.1152/ajpendo.00463.2007
  • Kemp, C. J., D'Alessio, D. A., Scott, R. O., Kelm, G. R., Meller, S. T., Barrera, J. G., Seeley, R. J., Clegg, D. J., & Benoit, S. C. (2008). Voluntary consumption of ethyl oleate reduces food intake and body weight in rats.. Physiology & Behavior, 93 (4-5), 912-8. doi:10.1016/j.physbeh.2007.12.008
  • Pfluger, P. T., Kirchner, H., Günnel, S., Schrott, B., Perez-Tilve, D., Fu, S., Benoit, S. C., Horvath, T., Joost, H., Wortley, K. E., Sleeman, M. W., & Tschöp, M. H. (2008). Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure.. American Journal of Physiology. Gastrointestinal and Liver Physiology, 294 (3), G610-8. doi:10.1152/ajpgi.00321.2007
  • Lo, C., Samuelson, L. C., Chambers, J. B., King, A., Heiman, J., Jandacek, R. J., Sakai, R. R., Benoit, S. C., Raybould, H. E., Woods, S. C., & Tso, P. (2008). Characterization of mice lacking the gene for cholecystokinin.. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 294 (3), R803-10. doi:10.1152/ajpregu.00682.2007
  • Reizes, O., Benoit, S. C., & Clegg, D. J. (2008). The role of syndecans in the regulation of body weight and synaptic plasticity.. The International Journal of Biochemistry & Cell Biology, 40 (1), 28-45. doi:10.1016/j.biocel.2007.06.011
  • Eric Hu, X., Wos, J. A., Dowty, M. E., Suchanek, P. M., Ji, W., Chambers, J. B., Benoit, S. C., Clegg, D. J., & Reizes, O. (2008). Small-molecule melanin-concentrating hormone-1 receptor antagonists require brain penetration for inhibition of food intake and reduction in body weight.. The Journal of Pharmacology and Experimental Therapeutics, 324 (1), 206-13. doi:10.1124/jpet.107.130435
  • Benoit, S. C., & Tracy, A. L. (2008). Behavioral controls of food intake.. Peptides, 29 (1), 139-47. doi:10.1016/j.peptides.2007.10.019
  • Davis, J. F., Melhorn, S. J., Shurdak, J. D., Heiman, J. U., Tschöp, M. H., Clegg, D. J., & Benoit, S. C. (2007). Comparison of hydrogenated vegetable shortening and nutritionally complete high-fat diet on limited access-binge behavior in rats.. Physiology & Behavior, 92 (5), 924-30. doi:10.1016/j.physbeh.2007.06.024
  • Davidson, T. L., Kanoski, S. E., Schier, L. A., Clegg, D. J., & Benoit, S. C. (2007). A potential role for the hippocampus in energy intake and body weight regulation.. Current Opinion in Pharmacology, 7 (6), 613-6. doi:10.1016/j.coph.2007.10.008
  • Nogueiras, R., Wiedmer, P., Perez-Tilve, D., Veyrat-Durebex, C., Keogh, J. M., Sutton, G. M., Pfluger, P. T., Castaneda, T. R., Neschen, S., Hofmann, S. M., Howles, P. N., Morgan, D. A., Benoit, S. C., Szanto, I., Schrott, B., Schürmann, A., Joost, H., Hammond, C., Hui, D. Y., Woods, S. C., Rahmouni, K., Butler, A. A., Farooqi, I. S., O'Rahilly, S., Rohner-Jeanrenaud, F., & Tschöp, M. H. (2007). The central melanocortin system directly controls peripheral lipid metabolism.. The Journal of Clinical Investigation, 117 (11), 3475-88. doi:10.1172/JCI31743
  • Clegg, D. J., Brown, L. M., Zigman, J. M., Kemp, C. J., Strader, A. D., Benoit, S. C., Woods, S. C., Mangiaracina, M., & Geary, N. (2007). Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats.. Diabetes, 56 (4), 1051-8. doi:10.2337/db06-0015
  • Brown, L. M., Benoit, S. C., Woods, S. C., & Clegg, D. J. (2007). Intraventricular (i3vt) ghrelin increases food intake in fatty Zucker rats.. Peptides, 28 (3), 612-6. doi:10.1016/j.peptides.2006.11.012
  • Pfluger, P. T., Kampe, J., Castaneda, T. R., Vahl, T., D'Alessio, D. A., Kruthaupt, T., Benoit, S. C., Cuntz, U., Rochlitz, H. J., Moehlig, M., Pfeiffer, A. F. H., Koebnick, C., Weickert, M. O., Otto, B., Spranger, J., & Tschöp, M. H. (2007). Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36.. The Journal of Clinical Endocrinology and Metabolism, 92 (2), 583-8. doi:10.1210/jc.2006-1425
  • Brown, L. M., Clegg, D. J., Benoit, S. C., & Woods, S. C. (2006). Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice.. Physiology & Behavior, 89 (5), 687-91. doi:10.1016/j.physbeh.2006.08.008
  • Duncan, E. A., Rider, T. R., Jandacek, R. J., Clegg, D. J., Benoit, S. C., Tso, P., & Woods, S. C. (2006). The regulation of alcohol intake by melanin-concentrating hormone in rats.. Pharmacology, Biochemistry, and Behavior, 85 (4), 728-35. doi:10.1016/j.pbb.2006.11.004
  • Davis, J. F., McQuade, J. M., Drazen, D. L., Woods, S. C., Seeley, R. J., & Benoit, S. C. (2006). Role for dopamine-3 receptor in the hyperphagia of an unanticipated high-fat meal in rats.. Pharmacology, Biochemistry, and Behavior, 85 (1), 190-7. doi:10.1016/j.pbb.2006.07.035
  • Sanna, B., Brandt, E. B., Kaiser, R. A., Pfluger, P., Witt, S. A., Kimball, T. R., van Rooij, E., De Windt, L. J., Rothenberg, M. E., Tschop, M. H., Benoit, S. C., & Molkentin, J. D. (2006). Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo.. Proceedings of the National Academy of Sciences of the United States of America, 103 (19), 7327-32. doi:10.1073/pnas.0509340103
  • Clegg, D. J., Brown, L. M., Woods, S. C., & Benoit, S. C. (2006). Gonadal hormones determine sensitivity to central leptin and insulin.. Diabetes, 55 (4), 978-87.
  • Diano, S., Farr, S. A., Benoit, S. C., McNay, E. C., da Silva, I., Horvath, B., Gaskin, F. S., Nonaka, N., Jaeger, L. B., Banks, W. A., Morley, J. E., Pinto, S., Sherwin, R. S., Xu, L., Yamada, K. A., Sleeman, M. W., Tschöp, M. H., & Horvath, T. L. (2006). Ghrelin controls hippocampal spine synapse density and memory performance.. Nature Neuroscience, 9 (3), 381-8. doi:10.1038/nn1656
  • Perez-Tilve, D., Nogueiras, R., Mallo, F., Benoit, S. C., & Tschoep, M. (2006). Gut hormones ghrelin, PYY, and GLP-1 in the regulation of energy balance [corrected] and metabolism.. Endocrine, 29 (1), 61-71.
  • Reizes, O., Clegg, D. J., Strader, A. D., & Benoit, S. C. (2006). A role for syndecan-3 in the melanocortin regulation of energy balance.. Peptides, 27 (2), 274-80. doi:10.1016/j.peptides.2005.02.030
  • Gotoh, K., Liu, M., Benoit, S. C., Clegg, D. J., Davidson, W. S., D'Alessio, D., Seeley, R. J., Tso, P., & Woods, S. C. (2006). Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake.. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 290 (1), R202-7. doi:10.1152/ajpregu.00502.2005
  • Boggiano, M. M., Chandler, P. C., Oswald, K. D., Rodgers, R. J., Blundell, J. E., Ishii, Y., Beattie, A. H., Holch, P., Allison, D. B., Schindler, M., Arndt, K., Rudolf, K., Mark, M., Schoelch, C., Joost, H. G., Klaus, S., Thöne-Reineke, C., Benoit, S. C., Seeley, R. J., Beck-Sickinger, A. G., Koglin, N., Raun, K., Madsen, K., Wulff, B. S., Stidsen, C. E., Birringer, M., Kreuzer, O. J., Deng, X. Y., Whitcomb, D. C., Halem, H., Taylor, J., Dong, J., Datta, R., Culler, M., Ortmann, S., Castañeda, T. R., & Tschöp, M. (2005). PYY3-36 as an anti-obesity drug target.. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity, 6 (4), 307-22. doi:10.1111/j.1467-789X.2005.00218.x
  • Davidson, T. L., Kanoski, S. E., Tracy, A. L., Walls, E. K., Clegg, D., & Benoit, S. C. (2005). The interoceptive cue properties of ghrelin generalize to cues produced by food deprivation.. Peptides, 26 (9), 1602-10. doi:10.1016/j.peptides.2005.02.014
  • Otto, B., Spranger, J., Benoit, S. C., Clegg, D. J., & Tschöp, M. H. (2005). The many faces of ghrelin: new perspectives for nutrition research?. The British Journal of Nutrition, 93 (6), 765-71.
  • Benoit, S. C., Clegg, D. J., Woods, S. C., & Seeley, R. J. (2005). The role of previous exposure in the appetitive and consummatory effects of orexigenic neuropeptides.. Peptides, 26 (5), 751-7. doi:10.1016/j.peptides.2004.12.012
  • Clegg, D. J., Benoit, S. C., Reed, J. A., Woods, S. C., Dunn-Meynell, A., & Levin, B. E. (2005). Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet.. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 288 (4), R981-6. doi:10.1152/ajpregu.00675.2004
  • Benoit, S. C., & Tschöp, M. H. (2005). PYY3-36 "monkeys around" with energy balance.. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 288 (2), R358-9. doi:10.1152/ajpregu.00755.2004
  • Woods, S. C., D'Alessio, D. A., Tso, P., Rushing, P. A., Clegg, D. J., Benoit, S. C., Gotoh, K., Liu, M., & Seeley, R. J. (2004). Consumption of a high-fat diet alters the homeostatic regulation of energy balance.. Physiology & Behavior, 83 (4), 573-8. doi:10.1016/j.physbeh.2004.07.026
  • Woods, S. C., Benoit, S. C., Clegg, D. J., & Seeley, R. J. (2004). Clinical endocrinology and metabolism. Regulation of energy homeostasis by peripheral signals.. Best Practice & Research. Clinical Endocrinology & Metabolism, 18 (4), 497-515. doi:10.1016/j.beem.2004.08.004
  • Strader, A. D., Reizes, O., Woods, S. C., Benoit, S. C., & Seeley, R. J. (2004). Mice lacking the syndecan-3 gene are resistant to diet-induced obesity.. The Journal of Clinical Investigation, 114 (9), 1354-60. doi:10.1172/JCI20631
  • Tschöp, M., Castañeda, T. R., Joost, H. G., Thöne-Reineke, C., Ortmann, S., Klaus, S., Hagan, M. M., Chandler, P. C., Oswald, K. D., Benoit, S. C., Seeley, R. J., Kinzig, K. P., Moran, T. H., Beck-sickinger, A. G., Koglin, N., Rodgers, R. J., Blundell, J. E., Ishii, Y., Beattie, A. H., Holch, P., Allison, D. B., Raun, K., Madsen, K., Wulff, B. S., Stidsen, C. E., Birringer, M., Kreuzer, O. J., Schindler, M., Arndt, K., Rudolf, K., Mark, M., Deng, X. Y., Whitcomb, D. C., Halem, H., Taylor, J., Dong, J., Datta, R., Culler, M., Craney, S., Flora, D., Smiley, D., Heiman, M. L., & Withcomb, D. C. (2004). Physiology: does gut hormone PYY3-36 decrease food intake in rodents?. Nature, 430 (6996), 1 p following 165; d. doi:10.1038/nature02665
  • Figlewicz, D. P., Bennett, J., Evans, S. B., Kaiyala, K., Sipols, A. J., & Benoit, S. C. (2004). Intraventricular insulin and leptin reverse place preference conditioned with high-fat diet in rats.. Behavioral Neuroscience, 118 (3), 479-87. doi:10.1037/0735-7044.118.3.479
  • McQuade, J., Benoit, S. C., Xu, M., Woods, S. C., & Seeley, R. J. (2004). High-fat diet induced adiposity in mice with targeted disruption of the dopamine-3 receptor gene.. Behavioural Brain Research, 151 (1-2), 313-9. doi:10.1016/j.bbr.2003.09.034
  • Benoit, S. C., Clegg, D. J., Seeley, R. J., & Woods, S. C. (2004). Insulin and leptin as adiposity signals.. Recent Progress in Hormone Research, 59, 267-85.
  • McQuade, J. M., Benoit, S. C., Woods, S. C., & Seeley, R. J. (2003). 7-OH-DPAT selectively reduces intake of both chow and high fat diets in different food intake regimens.. Pharmacology, Biochemistry, and Behavior, 76 (3-4), 517-23.
  • Benoit, S. C., Clegg, D. J., Barrera, J. G., Seeley, R. J., & Woods, S. C. (2003). Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII.. Diabetes, 52 (11), 2684-8.
  • McQuade, J., Xu, M., Woods, S. C., Seeley, R. J., & Benoit, S. C. (2003). Ethanol consumption in mice with a targeted disruption of the dopamine-3 receptor gene.. Addiction Biology, 8 (3), 295-303. doi:10.1080/13556210310001602202
  • Benoit, S. C., Air, E. L., Wilmer, K., Messerschmidt, P., Hodge, K. M. B., Jones, M. B., Eckstein, D. M. M., McOsker, C. C., Seeley, R. J., Woods, S. C., & Sheldon, R. J. (2003). Two novel paradigms for the simultaneous assessment of conditioned taste aversion and food intake effects of anorexic agents.. Physiology & Behavior, 79 (4-5), 761-6.
  • Clegg, D. J., Benoit, S. C., Air, E. L., Jackman, A., Tso, P., D'Alessio, D., Woods, S. C., & Seeley, R. J. (2003). Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII.. Endocrinology, 144 (7), 2941-6.
  • Reizes, O., Benoit, S. C., Strader, A. D., Clegg, D. J., Akunuru, S., & Seeley, R. J. (2003). Syndecan-3 modulates food intake by interacting with the melanocortin/AgRP pathway.. Annals of the New York Academy of Sciences, 994, 66-73.
  • Benoit, S. C., Sheldon, R. J., Air, E. L., Messerschmidt, P., Wilmer, K. A., Hodge, K. M. B., Jones, M. B., Eckstein, D. M. M., McOsker, C. C., Woods, S. C., & Seeley, R. J. (2003). Assessment of the aversive consequences of acute and chronic administration of the melanocortin agonist, MTII.. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity, 27 (5), 550-6. doi:10.1038/sj.ijo.0802280
  • Clegg, D. J., Riedy, C. A., Smith, K. A. B., Benoit, S. C., & Woods, S. C. (2003). Differential sensitivity to central leptin and insulin in male and female rats.. Diabetes, 52 (3), 682-7.
  • Clegg, D. J., Air, E. L., Benoit, S. C., Sakai, R. S., Seeley, R. J., & Woods, S. C. (2003). Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake.. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 284 (2), R494-9.
  • Benoit, S. C., McQuade, J., Clegg, D. J., Xu, M., Rushing, P. A., Woods, S. C., & Seeley, R. J. (2003). Altered feeding responses in mice with targeted disruption of the dopamine-3 receptor gene.. Behavioral Neuroscience, 117 (1), 46-54.
  • Clegg, D. J., Wortman, M. D., Benoit, S. C., McOsker, C. C., & Seeley, R. J. (2002). Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion.. Diabetes, 51 (11), 3196-201.
  • Benoit, S. C., Air, E. L., Coolen, L. M., Strauss, R., Jackman, A., Clegg, D. J., Seeley, R. J., & Woods, S. C. (2002). The catabolic action of insulin in the brain is mediated by melanocortins.. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience, 22 (20), 9048-52.
  • Air, E. L., Benoit, S. C., Clegg, D. J., Seeley, R. J., & Woods, S. C. (2002). Insulin and leptin combine additively to reduce food intake and body weight in rats.. Endocrinology, 143 (6), 2449-52.
  • Air, E. L., Benoit, S. C., Blake Smith, K. A., Clegg, D. J., & Woods, S. C. (2002). Acute third ventricular administration of insulin decreases food intake in two paradigms.. Pharmacology, Biochemistry, and Behavior, 72 (1-2), 423-9.
  • Air, E. L., Strowski, M. Z., Benoit, S. C., Conarello, S. L., Salituro, G. M., Guan, X., Liu, K., Woods, S. C., & Zhang, B. B. (2002). Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity.. Nature Medicine, 8 (2), 179-83. doi:10.1038/nm0202-179
  • Hagan, M. M., Rushing, P. A., Benoit, S. C., Woods, S. C., & Seeley, R. J. (2001). Opioid receptor involvement in the effect of AgRP- (83-132) on food intake and food selection.. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 280 (3), R814-21.
  • Hagan, M. M., Benoit, S. C., Rushing, P. A., Pritchard, L. M., Woods, S. C., & Seeley, R. J. (2001). Immediate and prolonged patterns of Agouti-related peptide-(83--132)-induced c-Fos activation in hypothalamic and extrahypothalamic sites.. Endocrinology, 142 (3), 1050-6.
  • Benoit, S. C., Schwartz, M. W., Lachey, J. L., Hagan, M. M., Rushing, P. A., Blake, K. A., Yagaloff, K. A., Kurylko, G., Franco, L., Danhoo, W., & Seeley, R. J. (2000). A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences.. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience, 20 (9), 3442-8.
  • Benoit, S. C., Thiele, T. E., Heinrichs, S. C., Rushing, P. A., Blake, K. A., & Steeley, R. J. (2000). Comparison of central administration of corticotropin-releasing hormone and urocortin on food intake, conditioned taste aversion, and c-Fos expression.. Peptides, 21 (3), 345-51.
  • Benoit, S. C., Morell, J. R., & Davidson, T. L. (1999). Lesions of the amygdala central nucleus abolish lipoprivic-enhanced responding during oil-predicting conditioned stimuli.. Behavioral Neuroscience, 113 (6), 1233-41.
  • Davidson, T. L., Altizer, A. M., Benoit, S. C., Walls, E. K., & Powley, T. L. (1997). Encoding and selective activation of "metabolic memories" in the rat.. Behavioral Neuroscience, 111 (5), 1014-30.
  • Benoit, S. C., & Davidson, T. L. (1996). Interoceptive sensory signals produced by 24-hr food deprivation, pharmacological glucoprivation, and lipoprivation.. Behavioral Neuroscience, 110 (1), 168-80.
  • Seeley, R. J., Benoit, S. C., & Davidson, T. L. (1995). Discriminative cues produced by NPY do not generalize to the interoceptive cues produced by food deprivation.. Physiology & Behavior, 58 (6), 1237-41.
  • McNamara, R. K., Ostrander, M., Abplanalp, W., Richtand, N. M., Benoit, S. C., & Clegg, D. J. Modulation of phosphoinositide-protein kinase C signal transduction by omega-3 fatty acids: implications for the pathophysiology and treatment of recurrent neuropsychiatric illness.. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 75 (4-5), 237-57. doi:10.1016/j.plefa.2006.07.009
  • Benoit, S. C., Tracy, A. L., Air, E. L., Kinzig, K., Seeley, R. J., & Davidson, T. L. The role of the hypothalamic melanocortin system in behavioral appetitive processes.. Pharmacology, Biochemistry, and Behavior, 69 (3-4), 603-9.
  • Cushing, C. C., Benoit, S. C., Peugh, J. L., Reiter-Purtill, J., Inge, T. H., & Zeller, M. H. Longitudinal trends in hedonic hunger after Roux-en-Y gastric bypass in adolescents.. Surgery For Obesity and Related Diseases : Official Journal of the American Society For Bariatric Surgery, 10 (1), 125-30. doi:10.1016/j.soard.2013.05.009
  • Cushing, C. C., Peugh, J. L., Brode, C. S., Inge, T. H., Benoit, S. C., & Zeller, M. H. Longitudinal trends in food cravings following Roux-en-Y gastric bypass in an adolescent sample.. Surgery For Obesity and Related Diseases : Official Journal of the American Society For Bariatric Surgery, 11 (1), 14-8. doi:10.1016/j.soard.2014.05.035
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Other Publications
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  • Davis JF, Krause EG, Sakai RR, Benoit SC(Under Review). Melanocortin modulation of food-induced conditioned place preference and sensitized feeding responses. .
  • Zheng Q, Zhu J, Shanabrough M, Borok E, Benoit DC, Clegg DJ, Horvath TL, Reizes O(Under Review). Syndecan-3 affects efferents of the melanocortin system in regulation of energy metabolism. .
  • Davis JF, Choi DL, Schurdak JD, Clegg DJ, Lipton JW, Figlewicz DP, Benoit SC(Under Review). Inhibition of midbrain leptin receptor expression augments sucrose reinforced behavior and mesolimbic dopamine in the rat. .
  • Summer SS, Brehm BJ, Benoit SC, D'Alessio D(In Progress). Adiponectin changes in relation to the macronutrient composition of a weight loss diet. .
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Book Chapter
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  • Benoit SC, Clegg DJ, Woods SC (2007). Energy Balance and FeedingIn JD Blaustein (Eds.) ,Handbook of Neurochemistry and Molecular Biology: Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology 3rd Edition(pp.619). NY :Springer Science.
  • Clegg DJ, Benoit SC, Reizes O (2007). Leptin Signaling in the BrainIn PA Donohoue (Eds.) ,Energy Metabolism and Obesity: Research and Clinical Applications (Contemporary Endocrinology)(pp.23). Totowa, NJ :Humana Press.
  • Reizes O, Benoit SC, Clegg DJ (2007). Neuroregulation of AppetiteIn Kushner RF & DH Bessesen (Eds.) ,Treatment of the Obese Patient (Contemporary Endocrinology)(pp.1). Totowa, NJ :Humana Press.
  • Tracy AL, Benoit SC (2008). Molecular mechanisms: The regulation of energy intakeIn MH Tschoep (Eds.) ,Obesitext. [Obesitext]
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Invited Presentations
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  • (2005). . ,Les Arcs, France.
  • (2005). . ,Guelph, ON.
  • (2005). . ,Pittsburgh, PA.
  • (2005). . ,Indianapolis, IN.
  • (2005). .Ascona Workshop. Ascona ,New York, NY.
  • (2005). .Vanderbilt University
  • (2006). . ,San Francisco, CA.
  • (2006). . ,Boston, MA.
  • (2006). . ,Atlanta, GA.
  • (2006). . ,Villars, Switzerland.
  • (2006). . ,Cincinnati, OH.
  • (2006). . ,Steamboat Springs, CO.
  • (2008). . ,Snowbird, UT.
  • (2008). . ,Les Arc, France.
  • (2008). . ,Okinawa, Japan.
  • (2008). . ,Cincinnati, OH.
  • (2008). .University of Washington ,Seattle, WA.
  • (2008). . ,San Francisco, CA.
  • (2009). . ,Switzerland.
  • (2009). . ,Frejus-Saint Raphael, France.
  • (2009). . ,Chicago, IL.
  • (2009). . ,Chicago, IL.
  • (2009). . ,Washington, D.C..
  • (2009). . ,Bethesda, MD.
  • (2009). . ,Snowmass Village, CO.
  • (2009). .University of Cincinnati
  • (2010). . , Ascona, Switzerland.
  • (2010). . ,Switzerland.
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Events Organized
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  • Winter Conference on Brain Research ,Conference(2010). Breckenridge, CO.
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Recent Awards/Honors
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  • Peptides.Gayle A. and Richard D. Olson Award for meritorious behavioral research,2005
  • Alan N. Epstein Research Award.Society for the Study of Ingestive Behavior. Award for a significant scientific achievement of an individual studying ingestive behavior less than 15 years after terminal degree.,2007
  • Role of Dietary Macronutrients in Stress and Cognition (Advisor).Oak Ridge Institute for Science and Education (ORISE) Fellowship to Dr. Andrea Tracy (DC).,2006
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Keywords
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  • Obesity,Learning,Neuroendocrinology
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Animal Protocols
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  • Principal Investigator
    Behavioral assay core05-04-12-01
    Approved     Exp. Date: 05/11/2020
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